Systems Biology as an Integrated Platform for Bioinformatics, Systems Synthetic Biology, and Systems Metabolic Engineering

نویسندگان
چکیده

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Systems Biology as an Integrated Platform for Bioinformatics, Systems Synthetic Biology, and Systems Metabolic Engineering

Systems biology aims at achieving a system-level understanding of living organisms and applying this knowledge to various fields such as synthetic biology, metabolic engineering, and medicine. System-level understanding of living organisms can be derived from insight into: (i) system structure and the mechanism of biological networks such as gene regulation, protein interactions, signaling, and...

متن کامل

Synthetic Biology: Engineering Biological Systems

On June 26, 2000, President Bill Clinton and Prime Minister Tony Blair, along with Francis Collins, director of the Human Genome Project at the NIH, and Craig Venter, president of Celera Genomics, announced the arrival of the genomic era with the sequencing of the first draft sequence of the human genome. With this wealth of information, scientists and policy-makers alike were eager to welcome ...

متن کامل

BacillOndex: An Integrated Data Resource for Systems and Synthetic Biology

BacillOndex is an extension of the Ondex data integration system, providing a semantically annotated, integrated knowledge base for the model Gram-positive bacterium Bacillus subtilis. This application allows a user to mine a variety of B. subtilis data sources, and analyse the resulting integrated dataset, which contains data about genes, gene products and their interactions. The data can be a...

متن کامل

Synthetic Biology: A Systems Engineering Perspective

In this work, we provide a review from a systems engineering perspective of some of the design challenges found in bio-molecular systems. In particular, we focus on the problem of modularity. If components behave modularity, that is, their behavior does not change upon interconnection, then one can predict the behavior of a circuit directly by the behavior of the composing units. We show how th...

متن کامل

An Executable Biology Methodology for Systems and Synthetic Biology

In this paper we introduce a stochastic executable biology methodology that can be used for systems and synthetic biology research. Our methodology is based on a rigorous computational formalism, P systems, that capture the three essential components of living systems: membranes, information molecules (e.g. DNA, RNA, amino acid sequences) and metabolism. The mathematical structure of our formal...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Cells

سال: 2013

ISSN: 2073-4409

DOI: 10.3390/cells2040635